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Suboxone 8 mg contains 8 mg of buprenorphine hydrochloride and 2mg of naloxone hydrochloride dihydrate. Buprenorphine is a partial agonist that affects the mu-opioid receptor and an antagonist acting at the kappa-opioid receptor while Naloxone is an antagonist working at the mu-opioid receptor. Click Below Icon For Order.